Stem Cells and Tissue Engineering: An Overview of Modern Advances and Discoveries related to Stem Cells that contribute to Replacement of Native Tissue

By |2020-02-03T15:37:54-05:00November 14th, 2017|Research|

Stem Cells and Tissue Engineering: An Overview of Modern Advances and Discoveries related to Stem Cells that contribute to Replacement of Native Tissue Johnson H and Gallicchio VS ABSTRACT The number of patients that need engineered tissue replacements is on the rise. Tissue engineering is a subset of the field of regenerative medicine that patients [...]

Therapeutic Effects of Aging Stem Cells – Journal of Stem Cell Research

By |2020-02-03T15:38:05-05:00November 14th, 2017|Research|

Therapeutic Effects of Aging Stem Cells Michelle T. Lussier, Vincent S. Gallicchio. ABSTRACT Have researchers stumbled upon a way to create our own fountain of youth? Stem cells are unspecialized cells in the body capable of self-renewal and differentiation, ultimately responsible for the regenerative capacities of our body’s tissues. Known changes that occur on the [...]

Why ‘Useless’ Surgery Is Still Popular – The New York Times

By |2020-02-03T15:38:33-05:00July 7th, 2017|Research|

Before a drug can be marketed, it has to go through rigorous testing to show it is safe and effective. Surgery, though, is different. The Food and Drug Administration does not regulate surgical procedures. So what happens when an operation is subjected to and fails the ultimate test — a clinical trial in which patients are randomly assigned to have it or not?

Umbilical Cord Stem Cells

By |2020-02-03T15:38:43-05:00July 7th, 2017|Research|

Human umbilical cord (UC) is a promising source of mesenchymal stem cells (MSCs). Apart from their prominent advantages, such as a painless collection procedure and faster self-renewal, UC-MSCs have shown the ability to differentiate into three germ layers, to accumulate in damaged tissue or inflamed regions, to promote tissue repair, and to modulate immune re- sponse. There are diverse protocols and culture meth-ods for the isolation of MSCs from the various compart-ments of UC, such as Wharton’s jelly, vein, arteries, UC lining and subamnion and perivascular regions. In this review, we give a brief introduction to various compart-ments of UC as a source of MSCs and emphasize the potential clinical utility of UC-MSCs for regenerative medicine and immunotherapy.

Third-trimester amnioitc fluid stem cells

By |2020-02-03T15:38:53-05:00July 7th, 2017|Research|

Endothelial dysfunction is found in different pathologies such as diabetes and renal and heart diseases, representing one of the major health problems. The reduced vasodilation of impaired endothelium starts a prothrombotic state associated with irregular blood flow. We aimed to explore the potential of amniotic fluid stem (AFS) cells as a source for regenerative medicine in this field; for the first time, we focused on third-trimester amniotic fluid AFS cells and compared them with the already-described AFS cells from the second trimester.

Stem Cell Use in Osteoporesis 2017

By |2020-02-03T15:39:04-05:00July 7th, 2017|Research|

Stem cell research arose from the need to explore new therapeutic possibilities for intractable and lethal diseases. Although musculoskeletal disorders are basically nonlethal, their high prevalence and relative ease of performing clinical trials have facilitated the clinical application of stem cells in this field. However, few reliable clinical studies have been published, despite the plethora of in vitro and preclinical studies in stem cell research for regenerative medicine in the musculoskeletal system.

Stem Cells for Spinal Cord Injury

By |2020-02-03T15:39:13-05:00July 7th, 2017|Research|

Stem cell therapy can be used for alleviating the neuropathic pain induced by spinal cord injuries (SCIs). However, survival and differentiation of stem cells following their transplantation vary depending on the host and intrinsic factors of the cell. Therefore, the present study aimed to determine the effect of stem cells derived from bone marrow (BM-MSC) and umbilical cord (UC-MSC) on neuropathic pain relief.

Stem Cell – Neuropathy

By |2020-02-03T15:39:23-05:00July 7th, 2017|Research|

Mesenchymal stem cells (MSCs) have been shown in animal models to attenuate chronic neuropathic pain. This preliminary study investigated if: i) injections of autologous MSCs can reduce human neuropathic pain and ii) evaluate the safety of the procedure. Methods: Ten subjects with symptoms of neuropathic trigeminal pain underwent liposuction.

Stem Cell for Fracture Repair

By |2020-02-03T15:39:34-05:00July 7th, 2017|Research|

Non-union due to large bone loss often causes significant long-term morbidity. We incor-porate the use of allogeneic umbilical cord-derived mesenchymal stem cells (UC-MSCs) as part of the diamond concept of regenerative medicine in a case of infected non-union fracture.


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